Associate Principal Scientist / Senior Scientist: Computational Chemistry

Senior Scientist: Computational Chemistry – 24 months consultant assignment – AstraZeneca

Join a world leading team in developing the next generation of small molecule and PROTACs medicines!

AstraZeneca R&D, Gothenburg, Sweden seeks to recruit into Computational Chemistry, BioPharma Chemistry, Discovery Sciences.

Mission

AstraZeneca is committed to the development of the next generation of innovative medicines. The Computational Chemistry team are using of state of the art in silico methods for molecular modelling, ligand design, property predictions and data analysis as an integral part of BioPharma drug discovery projects with a focus on small to medium sized molecules. The team operates in a highly cross disciplinary environment in close collaboration with scientists from the Chemistry, Translational, Bioscience, DMPK and Pharmaceutical Sciences departments to advance the BioPharma project pipeline.

Job description

As a Computational Chemist you will have a profound impact on multiple projects across the BioPharma portfolio. You will work collaboratively with medicinal chemists and multidisciplinary teams across all discovery phases. You will efficiently and proactively apply a full range of computational chemistry and AI approaches to deliver design, predictive models and SAR-analysis to improve potency, selectivity, activity and/or ADMET properties of our drug compounds.

You will help identify scientific improvement areas in computational sciences and assess their application to AstraZeneca projects, while contributing to new computational capabilities through collaboration with external partners and colleagues across AZ sites. The role offers opportunities to publish original research and reviews in peer reviewed journals and requires maintaining up to date awareness of the literature and developments in the field.

You’ll work alongside a large community of computational chemists across functions—spanning cheminformatics, molecular simulations, structure‑ and