Associate Scientist, Serology
About this role
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At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.
We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we’ve invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSK’s long history of vaccine development, to create globally leading viral capabilities and cutting-edge vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life.
In the plan to create a new hub for vaccine discovery in Cambridge, we are building new laboratories that will be focused on the development of state-of-the-art methods that will be supporting deep product understanding, process and product development, as well as testing of pre-clinical and clinical samples for new vaccines.
This is an Associate Scientist position on the Serology and Assay Development team in Viral Vaccines. You will help develop and execute serological assays to be used for the evaluation of vaccine candidates and therapeutics. You will bring knowledge of immunology and/or virology, and experience in executing biological assays, which provide critical information to enable strategic decision making by the project teams.
We are looking for a highly motivated, innovative scientist with experience in viral neutralization assays and/or Fc effector function assays who is willing to go the extra mile to contribute to multiple projects and help usher a wide variety of vaccine candidates and therapeutics through preclinical development.
Responsibilities
- Help develop, validate and execute serology-related assays to assess antibody responses
- Plan and execute viral neutralization assays
- Growing up and quantifying viral stocks
- Plan and execute ligand binding assays in multiple formats
- Analyze and interpret experimental data and document results in an electronic notebook in a detailed and concise manner
- Write detailed protocols, procedures and work instructions to support immunology assays
- Reporting of results in team meetings and cross-function and cross-department meetings
- Help with Lab management tasks including the ordering of materials, participation in operational meetings, routine equipment maintenance
- Contribute to the maintenance of a clean and safe workplace
- Basic Qualifications:
- Degree in Immunology, Virology, Microbiology, Pharmaceutical Sciences, or related scientific field
- MS with 0+ years of industry experience, or BS with 2+ years of lab experience.
- One or more years of experience in cell-based assays including viral neutralization assays or Fc effector function assays
- Preferred Qualifications:
- One or more years culturing, growing, and quantifying viral stocks
- At least one year of experience developing ligand binding assays or viral neutralization assays
- Prior experience with the implementation of robotic systems to increase analytical efficiencies
- Prior experience with the analysis of human biological samples (HBS) and knowledge of the HBS specific precautions
- Prior experience with developing analytical templates in SoftMax Pro, Prism and other analytical software
- Prior experience in statistical analysis
- Experience in qualification and/or validation of assays for regulatory filings
- Strong track-record of scientific publications in peer-reviewed journals or other demonstrations of scientific success
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