Global Study Manager - Haematology

“Are you ready to drive global clinical studies that truly change patients’ ‘lives”

At Acerta Pharma, a member of the AstraZeneca Group, we are dedicated to transforming the treatment landscape for patients with haematological malignancies. We are now looking for a proactive and globally minded Global Study Manager to join our Clinical Operations Team and take ownership of international haematology studies from early development through to late phase.

This is a high impact role with strong visibility, international collaboration, and personal development opportunities.

Global Study Manager

Haematology Clinical Operations | full time

Oss | Amsterdam

Acerta Pharma will be relocating to Amsterdam, with the current move planned for early 2027. Until that time, the working arrangement will be as follows: employees will work 1–2 days per week from the Oss location, 1–2 days from the Amsterdam office, and the remaining days from home. This schedule results in an overall office presence of 60%.

Your impact

As a Global Study Manager, you deliver delegated aspects of the clinical study in accordance with the Global Study Director (GSD) or Global Study Associate Director (GSAD).

Our portfolio ranges from First in Human and Phase I trials to Phase II and registrational studies. Your role will be aligned with the Study Team Operating Model for Insourced or Outsourced Delivery, current clinical trial regulations (e.g., ICH GCP), AstraZeneca Standard Operating Procedures (AZ SOPs).

You will:

Support & coordinate global haematology studies from protocol development through to CSR and archiving

Ensure the supply of Investigational product and study materials by liaising with Global Clinical Supply or external service providers as appropriate.

Supports GSADs in project management as per agreed delegation.

Support the study team in the implementation of audits and regulatory inspections.

Drive start-up activities and oversee early phase execution

Provide country and vendor oversight (e.g., imaging, labs, IRT, e-Pro, CRO)

Manage vendor contracts, budgets, and change orders

Oversee study documentation (ICF, CSA, country specific documents, vendor specifications)

Ensure inspection readiness through compliance to ICH-GCP and global regulations

Identify risks proactively and drive issue resolution across regions

Collaborate cross functionally with Clinical Operations, Regulatory, Data Management, Patient Safety, Supply Chain, and Procurement

Contribute to process improvements, innovation initiatives, and operational excellence.

This is a truly global remit, operating across all AstraZeneca countries.

Innovation & Digital mindset

We are accelerating digital transformation within Clinical Operations. Therefore, experience with AI tools, automation, or digital process optimisation is mandatory.

You bring:

Hands-on experience applying AI or automation in Clinical Operations

A mindset focused on efficiency, scalability, and smart data usage

The ability to identify opportunities to improve processes through technology

What do you bring?

Bachelor's / Master’s degree in Biomedical Sciences, Chemistry, Pharmacology, Life Science or related studies.

Minimum of 5 years of recent clinical research experience

At least 3 years of clinical development project management experience

Strong start up and phase I and/or phase II experience (phase III experience is a plus)

Therapeutic experience in haematology preferred

Vendor management experience

Excellent knowledge of ICH-GCP and global regulatory frameworks

Excellent communication and interpersonal skills.

Strong matrix leadership and stakeholder management skills

Strategic thinking with strong organisational and problem solving skills

Ability to manage competing priorities.

Fluent English (written & spoken)

Currently living in the Netherlands with a valid work permit

Location & office presence

Hybrid working model

Until we move to Amsterdam, currently scheduled for early 2027 (60% office based):

1-2 days per week in Oss

1-2 days per week in Amsterdam

Remaining days remote

After relocation:

60% office based in our new Amsterdam office

40% remote